Magnesium is nodig voor de energiestofwisseling in het lichaam, de overdracht van zenuwprikkels en het goed functioneren van de spieren. Verder geeft magnesium stevigheid aan het skelet en is het nodig voor de opbouw van onder andere spieren. Magnesium helpt ook mee aan een goede omzetting van voeding tot cellulaire energie.

Metingen van bloedwaarden magnesium zeggen weinig over de hoeveelheid magnesium in het lichaam omdat slechts 10% van de totale hoeveelheid magnesium extracellulair, in de bloedbaan gevonden wordt. Het lichaam houdt deze waarde zoveel mogelijk constant pas als door een flink tekort in het lichaam deze waarde niet meer op peil gehouden kan worden kan in het bloed een magnesiumtekort aangetoond worden doch het tekort is dan al heel fors.

De Gezondheidsraad heeft de aanbevolen dagelijkse hoeveelheid voor volwassen mannen (19-50 jaar) vastgesteld op 300-350 mg en voor volwassen vrouwen op 250-350 mg.

Bij een langdurig tekort aan magnesium treden klachten op als irritatie van de zenuwen in de spieren, hartritmestoornissen en maagkrampen.

Voldoende magnesium biedt volgens diverse onderzoeken bescherming tegen slapeloosheid, moeheid, osteoporose, zwangerschapsdiabetes, diabetes type-2 en hart- en vaatziektes. Doch 79% van de senioren ouder dan 55 jaar krijgen te weinig magnesium met hun voeding binnen, de gevolgen kunnen zijn; diabetes, hart- en vaatziektes en bijv. krampen in de benen. Zo geeft volgens onderzoek dagelijks minimaal 200 mg magnesium in de voeding de helft minder kans op diabetes type-2.
Magnesium speelt een belangrijke rol bij de insuline-afhankelijke glucose-opname uit het bloed. Het blijkt ook dat de magnesiumstatus bij diabetici lager ligt dan gemiddeld. Uit onderzoek komt in ieder geval naar voren dat magnesiumsuppletie kan helpen bij diabetes.
Uit een analyse van verschillende langlopende studies blijken de grote voordelen van voldoende magnesium in de voeding. Zo is de kans op het metaboolsyndroom duidelijk kleiner, ook op overgewicht, hoge bloeddruk en voldoende goed cholesterol (HDL). Bij extra inname van magnesium worden die voordelen nog eens versterkt en zijn ook de kans op verhoogde bloedwaarden geglyceerd hemoglobine kleiner, wat goed is tegen en bij diabetes.
Alhoewel gezonde botten voor een groot deel afhankelijk zijn van voldoende calcium en vitamine D blijkt een magnesium heel belangrijk te zijn voor een goed calciummetabolisme en om botbreuken te voorkomen. Zeker bij kleine kinderen lijkt magnesium volgens onderzoek nog belangrijker te zijn dan calcium. Onderzoek laat zien dat tekorten aan magnesium de effectiviteit van vitamine D danig kunnen verminderen. Hier nog een onderzoek die dat bevestigt.
Onderzoek laat zien dat het merendeel van de ouderen slaapproblemen blijkt te hebben die voor een groot deel veroorzaakt worden door een tekort aan calcium en magnesium waardoor je veel te vroeg wakker wordt en niet meer in slaap kunt komen. Belangrijk is dus gezonde en gevarieerde voeding te nemen en zonodig aan te vullen met magnesium.
Zij met te weinig magnesium in hun voeding hebben volgens onderzoek een flink grotere kans op een hartziekte en volgens een ander onderzoek een duidelijk grotere kans om dood te gaan.
Een studie onder ruim 153.000 postmenopauzale vrouwen laat zien dat voor deze vrouwen inname van voldoende magnesium in de voeding belangrijk is ter voorkoming van een fatale hartaandoening of een hartstilstand. Zij met de laagste (190mg/dag) inname van magnesium hadden wel 50-70% meer kans op een hartaandoening.
Magnesium verhindert de opname van aluminium en andere ongewenste stoffen zoals kwik, lood, cadmium en nikkel ter voorkoming van onder meer de ziekte van Alzheimer en de ziekte van Parkinson.
Voeding rijk aan kalium en magnesium is belangrijk tegen hoge bloeddruk, nog belangrijker dan natriumarme voeding (met weinig keukenzout).
Uit een voorlopige studie lijkt het dat voldoende magnesium in de voeding belangrijk is tegen cognitieve achteruitgang en de ziekte van Alzheimer.
In een studie onder ruim 66.000 vijftigplussers die 8 jaar lang gevolgd werden werd gekeken naar de inname van magnesium en de kans op alvleesklierkanker. Tegen het krijgen van alvleesklierkanker blijkt voldoende magnesium in de voeding zeer belangrijk te zijn. Tot een kwart minder magnesium in de voeding dan de aanbevolen dagelijkse hoeveelheid geeft al 40% meer kans op alvleesklierkanker. Gemiddeld gaf iedere 100 mg /dag minder magnesium 24% meer kans op alvleesklierkanker.
Magnesium is een mineraal in de voeding waarvan bekend is dat het zorgt voor goede zenuw- en spierfuncties, een goed hartritme, een goed immuunsysteem, sterke botten en belangrijk is voor wel ruim 300 biologische reacties in het lichaam. Uit een analyse van 34 studies blijkt dat voeding rijk aan magnesium (ca. 368 mg/dag) ook kan zorgen voor een lagere bloeddruk.
Uit een grote analyse blijkt weer eens het belang van voldoende magnesium in de voeding. Voldoende magnesium in de voeding is belangrijk ter voorkoming van hart- en vaatziektes, diabetes, een beroerte en doodgaan. Iedere 100 mg magnesium dagelijks extra geeft wel 22% minder kans op hartfalen, 7% minder kans op een beroerte, 19% minder kans op diabetes en 10% minder kans om dood te gaan.
Uit een studie onder deelnemers met een matige depressie blijkt dat dagelijkse inname van extra magnesium een veilig en effect middel kan zijn voor de behandeling van een milde tot matige depressie. Bij alle deelnemers werden zes weken inname van een magnesiumsupplement (per dag een supplement van 2 gram met daarin 250 mg magnesium) vergeleken met zes weken zonder supplement. Uit de studie blijkt dat extra magnesium zorgt voor een duidelijke verbetering van depressie- en angstsymptomen en dat al na 2 weken.
Een studie onder ruim 153.000 postmenopauzale vrouwen laat zien dat voor deze vrouwen inname van voldoende magnesium in de voeding belangrijk is ter voorkoming van een fatale hartaandoening of een hartstilstand. Zij met de laagste (190mg/dag) inname van magnesium hadden wel 50-70% meer kans op een hartaandoening.
Zowel hoge als lage bloedwaarden magnesium, waarden < 0,79 mmol/l (1,92 mg/dl) of > 0,90 mmol/l (2,19 mg/dl) doen volgens onderzoek de kans op dementie duidelijk vergroten.
Voeding rijk aan calcium en ook magnesium doet volgens onderzoek de kans op slokdarmkanker duidelijk verlagen. Weinig calcium en veel magnesium daarentegen verhoogt de kans.
Let op: Het langdurig gebruik van maagzuurremmers in de vorm van protonpompremmers. die veel gebruikt worden voor de behandeling van een maagzweer of bij brandend maagzuur, zorgen voor een duidelijk afname van de opname van belangrijke voedingsnutriënten, vitamines en mineralen zoals magnesium, calcium en vitamine B12.

Magnesiumsupplement in de wateroplosbare vorm van magnesium-malaat, -chloride, -lactaat, -citraat en -glycinaat worden voor zo'n 30% opgenomen in het lichaam en dat is volgens onderzoek een wel 4 keer betere opname dan de niet oplosbare vorm magnesium-oxide. Dit komt omdat het niet oplosbare magnesium-oxide eerst door maagzuur geneutraliseerd moet worden om opgenomen te kunnen worden.
De opname wordt meestal nog verbetert door de inname van vitamine B6 en zink.

Tekorten aan magnesium en zink doen de aanmaak van glutathion in het lichaam remmen.

Gelijktijdige inname van voedingsvezels en fosfor (bijv. uit frisdranken) verminderen de opname van magnesium.

Beter ook niet magnesium samen met calcium innemen omdat dan de opname van magnesium sterk geremd wordt.

Meer info over magnesium.

Meer info over magnesium door Natura Foundation.

Algemene opmerking:

Magnesium Offers Strong Radiation Protection
One would not normally think that magnesium deficiency can increase the risk of cancer yet we will find that just as severe dehydration or asphyxiation can cause death, magnesium deficiency can lead directly to cancer. It is known that carcinogenesis induces magnesium distribution disturbances, causing magnesium mobilization through blood cells and magnesium depletion in non-neoplastic tissues. Magnesium deficiency is carcinogenic, and in the case of solid tumors, a high level of supplemented magnesium inhibits carcinogenesis.

Researchers from Japan's National Cancer Center in Tokyo have found that an increased intake of magnesium reduces a man's risk of colon cancer by over 50 percent. Several studies have shown an increased cancer rate in regions with low magnesium levels in soil and drinking water. In Egypt the cancer rate was only about 10 percent of that in Europe and America. In the rural fellah it was practically non-existent. The main difference was an extremely high magnesium intake of 2.5-3g in these cancer-free populations, ten times more than in most western countries.

For all of these reasons and a hundred more, magnesium oil remains the number one item in my cancer protocol and thus number one for radiation exposure. Magnesium is our first line of defense against both.

"In the years leading up to Chernobyl, some dairy farmers in Austria were using remineralization as a part of their operations. They added rock dust to liquid manure as well as combining it with compost, thereby removing odors and greatly increasing soil biota. As a result, cows had twice the normal lifespan and produced much more milk. Amazingly enough, after Chernobyl, the cheeses that were remineralized (as well as biodynamic cheeses) measured no radioactivity whatsoever. Austrians would stand in long lines in order to buy these safe, remineralized products," writes Joanna Campe.

Iodine is obviously not the only substance that we should run to in the face of increasing radiation threats. Magnesium is a vital mineral whose lack leaves us open to not only radioactive damages but also those from heavy metals and thousands of chemicals, which we are commonly exposed to. Mercury and now a long list of radioactive particles are floating in the environment like invisible clouds that have spread out everywhere. They are raining down on us, damaging and damning our future. We can no longer be passive about building our defenses against the toxic onslaught.

Without sufficient magnesium, the body accumulates toxins and acid residues, degenerates rapidly, and ages prematurely.

Just about everyone who is writing protocols for radiation toxicity is forgetting about the importance of magnesium salts. Worse still are governments and the entire institution of medicine that are purposely ignorant about magnesium, so they cannot possibly be trusted for valuable health and medical information that will help us in our time of dire need. The need was dire before Fukushima but they did not want to admit that; they let the public get obsessed with CO2 emissions and said nothing about the mercury. Now with radioactive nuclides steadily building up in the background, we are in trouble than any of us care to admit. Today the situation has gone nuclear and there has never before been a need so great for detoxification and chelation.

Magnesium is a crucial factor in the natural self-cleansing and detoxification responses of the body. Magnesium is also necessary for effective chelation. It stimulates the sodium potassium pump on the cell wall and this initiates the cleansing process in part because the sodium-potassium-ATPase pump regulates intracellular and extracellular potassium levels. The healthy cell wall favors intake of nutrients and elimination of waste products.

The involvement of free radicals in tissue injury induced by magnesium deficiency causes an accumulation of oxidative products in heart, liver, kidney, skeletal muscle tissues and in red blood cells, leaving them more vulnerable to oxidative stress caused by radiation exposure. Both radiation exposure and heavy metals produce oxidative stress through the creation of increased levels of reactive oxygen species (ROS -- oxygen free radicals, peroxides, and singlet oxygen). It is known that these increased levels of intracellular ROS are sufficient to trigger apoptosis (cell death).

Glutathione is Magnesium-Dependent

Glutathione protects the cells from oxidative-stress-induced apoptosis and glutathione levels are magnesium dependent! "Glutathione is a very important detoxifying agent, enabling the body to get rid of undesirable toxins and pollutants. It forms a soluble compound with the toxin that can then be excreted through the urine or the gut. The liver and kidneys contain high levels of glutathione as they have the greatest exposure to toxins. The lungs are also rich in glutathione partly for the same reason. Many cancer-producing chemicals, heavy metals, drug metabolites etc. are disposed of in this way," says Dr. Patricia Kongshavn, former professor, department of medicine at McGill University.

Glutathione synthetase requires γ-glutamyl cysteine, glycine, ATP, and magnesium ions to form glutathione. In magnesium deficiency, the ss y-glutamyltranspeptidase is lowered. There is a direct relationship between cellular magnesium, GSH/GSSG ratios, and tissue glucose metabolism. Magnesium deficiency causes glutathione loss and this is unwelcome as the clouds of radiation are touching down across the northern hemisphere. Magnesium deficiency causes glutathione loss, which is not at all healthy because glutathione helps to defend the body against damage from cigarette smoking, exposure to radiation, cancer chemotherapy, and toxins such as alcohol and just about everything else.

According to Dr. Russell Blaylock, low magnesium is associated with dramatic increases in free radical generation as well as glutathione depletion and this is vital since glutathione is one of the few antioxidant molecules known to neutralize mercury. "For every molecule of pesticide that your body detoxifies, you throw away or use up forever a molecule of glutathione, magnesium and more," says Dr. Sherry Rogers who goes on to say that, "Your body uses nutrients to make this glutathione and it uses up energy as well. Every time we detoxify a chemical, we use up, lose, throw away forever, a certain amount of nutrients."

Mineral Deficiencies

Deficiencies in basic minerals like magnesium and selenium can make all the difference between health and disease, between being able to withstand chemical, heavy metal and radiation exposure. Dr. Rogers has indicated that there is as much as a 500-fold difference in the ability of individuals to detoxify the same chemicals and much of that will be true for radiation as well. A key marker of this difference is each individual's magnesium level. Deficiencies in magnesium will wreak havoc with our body's ability to detoxify and chelate heavy radioactive particles and explains much of the difference between one person withstanding radiation exposures and another person falling to radiation sickness.

Dr. Leslie Fisher has treated in excess of 35,000 patients where mineral therapy was prescribed as the sole form of medication. He has conducted research within his own clinics and the Department of Psychiatry, Austin Hospital, Melbourne. Mineral therapy is the foundation upon which chelation treatments and protocols are built. Magnesium does protect cells from aluminum, mercury, lead, cadmium, beryllium and nickel, which explains why re-mineralization is so essential for heavy metal detoxification and chelation as well as radiation protection. Magnesium is essential for the survival of our cells but takes on further importance now where our bodies are being bombarded on a daily basis with heavy metals and radiation.

Radiation and Diabetes

No one is going to convince the public that the increasing radiation will have a general effect on our health that can be easily traced back to the source. Even before we get cancer from radiation we have a general down-spiraling of body functions because of all the oxidative stress. In my book, New Paradigms in Diabetes, I write extensively about the direct relationship between magnesium deficiency and the onset of diabetes.

Pancreatic beta cells are sensitive to reactive oxygen species (ROS) attack when they are exposed to oxidative stress, because of the relatively low expression of antioxidant enzymes such as catalase and glutathione peroxidase. Diabetes is typically accompanied by increased production of free radicals and/or impaired antioxidant defense capabilities, indicating a central contribution of reactive oxygen species. It is also a fact that ROS is one of the major factors that induce oxidative modification of DNA and gene mutation.

The Chernobyl incident was a major disaster of humanity, which has resulted in a plethora of health problems that are still far from being fully recognized. Most studies analyzing the medical consequences of this catastrophe have so far focused on diseases such as thyroid cancer, leukemia, immune and autoimmune pathology, even though an increase in the incidence of type 1 diabetes mellitus, a disorder involving the immune system, was observed within the residential population of Hiroshima among survivors of the atom bomb detonation. Studies have also shown that thymectomy and a sub-lethal dose of gamma radiation induces type 1 diabetes in rats.

Researchers at the Pediatric Hospital A. Meyer, Florence, Italy studied this question by assessing the incidence of the disease in children in Gomel, Belarus in the years subsequent to the Chernobyl disaster. The results of the study seem to confirm the hypothesis that environmental pollution such as that subsequent to the Chernobyl accident can cause diabetes.

Mass screening for diabetes mellitus has been conducted on 64,000-113,000 atomic bomb survivors residing in Hiroshima City since 1961. From 1971 to 1992 a 2.7-fold increase in the prevalence of diabetes mellitus was observed in males and a 3.2-fold increase in females.

We have a significant and documented increase in the incidence of type 1 diabetes in children and adolescents after Chernobyl in the radioactively contaminated area of Gomel compared to Minsk.
- Heinrich Heine University

When beginning to build a protocol against the radiation and heavy metal onslaught, we need to stick with the basics and they are magnesium, iodine, sodium bicarbonate, vitamin C, selenium, clay, THC (cannabis),? as well as a natural chelator and superfoods. Properly filtered water also is essential. There is always more we can do but even affording these basics is a challenge to many.

Magnesium: The Lamp of Life
by Mark Sircus Ac., OMD

Inside chlorophyll is the lamp of life and that lamp is magnesium. The capture of light energy from the sun is magnesium dependent. Magnesium is bound as the central atom of the porphyrin ring of the green plant pigment chlorophyll. Magnesium is the element that causes plants to be able to convert light into energy and chlorophyll is identical to hemoglobin except the magnesium atom at the center has been taken out and iron put in. The whole basis of life and the food chain is seen in the sunlight-chlorophyll-magnesium chain. Since animals and humans obtain their food supply by eating plants, magnesium can be said to be the source of life for it is at the heart of chlorophyll and the process of photosynthesis.

A huge step forward for early life was the development of chlorophyll, a molecule that captures light energy from the sun in a process called photosynthesis. Chlorophyll systems convert energy from visible light into small energy-rich molecules easy for cells to use. The harnessing of the energy of visible light led to a vast expansion of early life-forms. Fossilized layers, three and half billion years old, have been found with evidence of blue-green algae that lived on top of tidal rocks.

Magnesium is needed by plants to form chlorophyll which is the substance that makes plants green. Without magnesium sitting inside the heart of chlorophyll, plants would not be able to take nutrition from the sun because the process of photosynthesis would not go on. When magnesium is deficient things begin to die. In reality one cannot take a breath, move a muscle, or think a thought without enough magnesium in our cells. Because magnesium is contained in chlorophyll it is considered an essential plant mineral salt.

Without chlorophyll, plants are unable to convert sunlight and carbon dioxide. There is no life without magnesium.

Magnesium is a necessary element for all living organisms both animal and plant. Chlorophyll is structured around a magnesium atom, while in animals, magnesium is a key component of cells, bones, tissues and just about every physiological process you can think of. Magnesium is primarily an intracellular cation; roughly 1% of whole-body magnesium is found extracellularly, and the free intracellular fraction is the portion regulating enzyme pathways inside the cells. Life packs the magnesium jealously into the cells, every drop of it is precious.

Insulin and Magnesium

Magnesium is necessary for both the action of insulin and the manufacture of insulin.

Magnesium is a basic building block to life and is present in ionic form throughout the full landscape of human physiology. Without insulin though, magnesium doesn't get transported from our blood into our cells where it is most needed. When Dr. Jerry Nadler of the Gonda Diabetes Center at the City of Hope Medical Center in Duarte, California, and his colleagues placed 16 healthy people on magnesium-deficient diets, their insulin became less effective at getting sugar from their blood into their cells, where it's burned or stored as fuel. In other words, they became less insulin sensitive or what is called insulin resistant. And that's the first step on the road to both diabetes and heart disease.

Insulin is a common denominator, a central figure in life as is magnesium. The task of insulin is to store excess nutritional resources.
This system is an evolutionary development used to save energy and other nutritional necessities in times (or hours) of abundance in order to survive in times of hunger. Little do we appreciate that insulin is not just responsible for regulating sugar entry into the cells but also magnesium, one of the most important substances for life. It is interesting to note here that the kidneys are working at the opposite end physiologically dumping from the blood excess nutrients that the body does not need or cannot process in the moment.

Controlling the level of blood sugars is only one of the many functions of insulin. Insulin plays a central role in storing magnesium but if our cells become resistant to insulin, or if we do not produce enough insulin, then we have a difficult time storing magnesium in the cells where it belongs. When insulin processing becomes problematic magnesium gets excreted through our urine instead and this is the basis of what is called magnesium wasting disease.

There is a strong relationship between magnesium and insulin action. Magnesium is important for the effectiveness of insulin. A reduction of magnesium in the cells strengthens insulin resistance.

Low serum and intracellular magnesium concentrations are associated with insulin resistance, impaired glucose tolerance, and decreased insulin secretion. Magnesium improves insulin sensitivity thus lowering insulin resistance. Magnesium and insulin need each other. Without magnesium, our pancreas won't secrete enough insulin--or the insulin it secretes won't be efficient enough--to control our blood sugar.

Magnesium in our cells helps the muscles to relax but if we can't store magnesium because the cells are resistant then we lose magnesium which makes the blood vessels constrict, affects our energy levels, and causes an increase in blood pressure. We begin to understand the intimate connection between diabetes and heart disease when we look at the closed loop between declining magnesium levels and declining insulin efficiency.

Though it would be a long stretch of the longest giraffe's neck to compare insulin with chlorophyll we are walking a trail at the very nuclear core of life. It's the magnesium trail and we find to our surprise that it takes us into intimate contact with the very structure and foundation of life. The dedication of this chapter is to the beauty of magnesium, to its meaning in life, in health and in medicine.

We were talking about chlorophyll and now insulin and putting magnesium in-between. Walking further along is the DHEA magnesium story and the DNA magnesium story. And then there is the cholesterol magnesium story. Every part of life is in love with magnesium except allopathic medicine which just cannot accept it in all its light, flame and beauty. Thousands of years ago the Chinese named it the beautiful metal and they were seeing something pharmaceutical medicine does not want to see for there is little money to be made from something so common.

Magnesium and DNA

Magnesium ions play critical roles in many aspects of cellular metabolism. Magnesium stabilizes structures of proteins, nucleic acids, and cell membranes by binding to the macromolecule's surface and promote specific structural or catalytic activities of proteins, enzymes, or ribozymes. Magnesium has a critical role in cell division. It has been suggested that magnesium is necessary for the maintenance of an adequate supply of nucleotides for the synthesis of RNA and DNA.

Magnesium plays a critical role in vital DNA repair proteins.
Magnesium ions synergetic effects on the active site geometry may affect the polymerase closing/opening trends.
Single-stranded RNA are stabilized by magnesium ions.

Distinct structural features of DNA, such as the curvature of dA tracts, are important in the recognition, packaging, and regulation of DNA are magnesium dependent. Physiologically relevant concentrations of magnesium have been found to enhance the curvature of dA tract DNAs. The chemistry of water activated by a magnesium ion is central to the function of the DNA repair proteins, apurinic/apyrimidic endonuclease 1 (Ape1) and polymerase A (Pol A). These proteins are key constituents of the base excision repair (BER) pathway, a process that plays a critical role in preventing the cytotoxic and mutagenic effects of most spontaneous, alkylation, and oxidative DNA damage.

Magnesium ions help guide polymerase selection for the correct nucleotide extends descriptions of polymerase pathways.

Dr. Paul Ellis informs us that, "Magnesium ions are central to the function of the DNA repair proteins, apurinic/apyrimidic endonuclease 1 (Ape1) and polymerase A (Pol A). These proteins are key constituents of the base excision repair (BER) pathway, a process that plays a critical role in preventing the cytotoxic and mutagenic effects of most spontaneous, alkylation, and oxidative DNA damage." DNA polymerase is considered to be a holoenzyme since it requires a magnesium ion as a co-factor to function properly. DNA-Polymerase initiates DNA replication by binding to a piece of single-stranded DNA. This process corrects mistakes in newly-synthesized DNA.

DHEA – Magnesium - Cholesterol

Low levels of DHEA are associated with loss of "pathology preventing" signaling between immune system cells.

Dr. James Michael Howard says, "Cancer and infections are both increasing and one of the basic reasons is reduced availability of DHEA, which stems from magnesium deficiency." Also known as "mother of all steroid hormones" DHEA is converted in the body into several different hormones, including estrogen and testosterone. DHEA appears to restore immune balance and stimulate monocyte production (the cells that attack tumors), B-cell activity (the cells that fight disease-causing organisms), T-cell mobilization (infection fighting T-cells have DHEA binding sites), and protection of the thymus gland (which produces T-cells). The data suggest that DHEA has a role in the neuro-endocrine regulation of the antibacterial immune resistance.

All steroid hormones are created from cholesterol in a hormonal cascade. Cholesterol, that most maligned compound, is actually crucial for health and is the mother of hormones from the adrenal cortex, including cortisone, hydrocortisone, aldosterone, and DHEA. Cholesterol cannot be synthesized without magnesium and cholesterol is a vital component of many hormones. These hormones are interrelated, each performing a unique biological function with them all depending on magnesium for their function. Aldosterone interestingly needs magnesium to be produced and it also regulates magnesium's balance.

Dr. Mildred S. Seelig wrote, "Mg2+-ATP is the controlling factor for the rate-limiting enzyme in the cholesterol biosynthesis sequence that is targeted by the statin pharmaceutical drugs, comparison of the effects of Mg2+ on lipoproteins with those of the statin drugs is warranted. Formation of cholesterol in blood, as well as of cholesterol required in hormone synthesis, and membrane maintenance, is achieved in a series of enzymatic reactions that convert HMG-CoA to cholesterol. The rate-limiting reaction of this pathway is the enzymatic conversion of HMG CoA to mevalonate via HMG CoA. The statins and Mg inhibit that enzyme. Mg has effects that parallel those of statins. For example, the enzyme that deactivates HMG-CoA Reductase requires Mg, making Mg a Reductase controller rather than inhibitor. Mg is also necessary for the activity of lecithin cholesterol acyl transferase (LCAT), which lowers LDL-C and triglyceride levels and raises HDL-C levels."

Desaturase is another Mg-dependent enzyme involved in lipid metabolism which statins do not directly affect.

DHEA is a steroid hormone produced by the adrenal gland and ovaries and converted to testosterone and estrogen. After being secreted by the adrenal glands, it circulates in the bloodstream as DHEA-sulfate (DHEAS) and is converted as needed into other hormones. Magnesium chloride, when applied transdermally, is reported by Dr. Norman Shealy to increase DHEA. Dr. Shealy has determined that when the body is presented with adequate levels of magnesium at the cellular level, the body will begin to naturally produce DHEA and also DHEA-S.
Transdermal is the ultimate way to replenish cellular magnesium levels. Every cell in the body bathes and feeds in it and even DHEA
levels are increased naturally, according to Dr. Norman Shealy.
This effect is not seen in oral or intravenous magnesium administration and Dr. Shealy has a patent pending in this area. It is thought that transdermal application interacts in some way with the fatty tissues of the skin to create the affect. Studies link low levels of DHEA to chronic inflammation, immune dysfunction, depression, rheumatoid arthritis, Type-II diabetic complications, greater risk for certain cancers, heart disease and osteoporosis.

Magnesium and Glutathione

Without sufficient magnesium, the body accumulates toxins and acid residues, degenerates rapidly, and ages prematurely.

According to Dr. Russell Blaylock, low magnesium is associated with dramatic increases in free radical generation as well as glutathione depletion and this is vital since glutathione is one of the few antioxidant molecules known to neutralize mercury. Glutathione requires magnesium for its synthesis. Glutathione synthetase requires γ-glutamyl cysteine, glycine, ATP, and magnesium ions to form glutathione.

In magnesium deficiency, the enzyme y-glutamyl transpeptidase is lowered. Data demonstrates a direct action of glutathione both in vivo and in vitro to enhance intracellular magnesium and a clinical linkage between cellular magnesium, GSH/GSSG ratios, and tissue glucose metabolism. Magnesium deficiency causes glutathione loss, which is not affordable because glutathione helps to defend the body against damage from cigarette smoking, exposure to radiation, cancer chemotherapy, and toxins such as alcohol and just about everything else.

Scientific Miracles in Medicine

The 21st century is seeing the plagues of diabetes, heart disease, cancer and neurological diseases explode with the entire western medical establishment confused about even the most basic health issues. The three trillion dollar medical machine in the United States is impotent against chronic diseases and is responsible itself for much of the horror that is happening.

Medical basics, we have to get back to them returning to the understanding of the simplest things like water. What do you give a person coming out of a week long walk in the desert without water? A coke? Do we have to do a thousand double blind studies to realize there is only one answer? Are we that dumb that medicine cannot see the forest from the trees?

When someone is in cardiac arrest or are having a stroke, having panic attacks with heart palpitations what is the first thing, the very first thing we would reach for like one would reach for a six shooter? Our biological engine is seizing up what do we do? For the next million years there is going to be only one answer and that answer is magnesium preferably in the chloride form. It will never change either for that person coming out of the desert; water will always be the answer to the need. We are talking so close to the source of life when talking about water or magnesium. But unfortunately there will always be those who think giving a coke to a very thirsty person is just fine and doctors who think they can forget about nature and try to substitute something to stand in magnesium's place.

The bedrock of medical truth sits upon the metal magnesium for it is at the exact center of biological life like air and water is. All of life collapses around its loss, but with only the smallest amount of caring and intelligence we can replete what has been lost inside of a person's cells. The realization that magnesium is at the center of life in chlorophyll should help us place magnesium in the temple it deserves. It is the ultimate love drug when used as a medicine. It's the first thing you give a person if you want to give something necessary and helpful.

It will take this entire book to present all the reasons that magnesium qualifies as a love drug; there are reasons that take us out of the physical body and into emotional, mental and spiritual bodies. Psychologists and psychiatrists also have to discover magnesium for it offers them a tool they have not found anywhere else. Magnesium is the Lamp of Life; it operates at the core of physiology offering us what can only be called scientific miracles in medicine. Though other substances like Vitamin C or even iodine are powerful competitors they cannot compare in sheer healing horsepower to magnesium.

Magnesium Medicine

It is no exaggeration for me to say that magnesium saved my life. But is ironic that I am the one saying it, because during my diverse medical career in general medicine, my greatest expertise has always been prescription drugs, not natural supplements. Dr. Jay S. Cohen.

The Magnesium Solution for High Blood Pressure

Magnesium serves hundreds of important functions in the body and for that reason it has virtually no side effects. Researchers all over the world have confirmed its vital role yet, despite the intensive scientific brainpower that has been directed toward magnesium most doctors know hardly anything about it and never consider magnesium for treating patients. Magnesium comes to us with scientific evidence that dwarfs the evidence presented by pharmaceutical companies for any of their prescription drugs but its use is still contained. (See chapter on why doctors do not use more magnesium)

Magnesium chloride treatments address systemic nutritional deficiencies, act to improve the function of our cells and immune system, and help protect cells from oxidative damage. Its a systemic medicine as well as a local one bringing new life and energy to the cells wherever it is applied topically. When used with oral administration, transdermal magnesium therapy offers us the opportunity to get dosages up to the powerful therapeutic range without compromising intestinal comfort through oral use alone.

What we have found is that magnesium chloride, applied transdermally, is the ideal magnesium delivery system - with health benefits unequalled in the entire world of medicine.

Magnesium chloride solutions offer a medical miracle to humanity, one that many have sought but have not found. In fact Dr. Carolyn Dean, titled her book The Magnesium Miracle and she could not have been more correct. Nothing short of a miracle is to be expected with increases in the cellular levels of magnesium if those levels have been depleted.

There is no wonder drug that can claim, in the clear, what magnesium chloride can do. Most people will show dramatic improvements in the state of their health when they replete their magnesium levels and the very best way to do that is with magnesium chloride applied transdermally (baths and body spraying), orally, vaporized into the lungs, diluted for use with ones eyes, intravenously, and even in douches and enemas.

Constant magnesium massages are what kings and queens should be dreaming of.
With such "brine solutions" the concentrate can simply be applied to the skin or poured into bath water, and in an instant we have a medical treatment without equal in the world of medicine. Intensive transdermal and oral magnesium therapy can be safely applied every day for constantly strengthened health.

Hidden in each cubic mile of ocean water is enough healing power to put the pharmaceutical companies out of business.

And there are medical reasons why we love the beach and ocean. Intensive magnesium baths, aerosolized iodine, vitamin D natural style and grounding to the earth through the sand. Medical science and the pharmaceutical companies will eventually have to deal with the fact that the most powerful and universal medicine on earth is a basic nutrient from the sea and can be purchased by anyone at low cost.

Magnesium is nothing short of a miracle to a person deficient in this mineral. So clear and observable are the effects that there is no mistake, no mysticism, no false claim made.
Emergency room personnel know of this and use either magnesium sulfate or chloride to save peoples lives during heart attacks or to diminish the damage from strokes. And new research suggests that MgSO4 infusions may have a role in cerebral vasospasm prophylaxis if therapy is initiated within 48 hours of aneurysm rupture.

Medicine today is more and more frequently described in terms of science. With the origin and development of drugs and surgical techniques, modern medicine has thought itself to be evermore exact and evermore resembling the hard sciences of chemistry and physics. In the case of magnesium, medicine has fallen from the grace of the pure sciences, which insists that they are ignoring the best medicine available anywhere. Magnesium is clearly evidence-based medicine but the quality of the evidence used pharmaceutical medicine is highly suspect. There is no such cloud of doubt hanging over the scientific evidence that makes it clear why magnesium would be both potent and safe.

When it comes to cardiac disease we create our primary protocol around magnesium, selenium and iodine. These three core minerals, when backed up with a strong naturopathic protocol, which includes natural mercury detoxification of the heart tissues, will transform cardiology into a field of medicine that does not have its patients dying like flies.

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(25-05-2020)