Meer vis tegen depressies tijdens zwangerschap*
Uit een kleine studie blijkt dat het regelmatig eten van vis
en dan vooral vette, de kans op een depressie tijdens en na de
zwangerschap zou kunnen verminderen. In een eerdere studie hadden de wetenschappers al vastgesteld dat voldoende
omega-3 vetzuren tijdens de
zwangerschap zorgt voor een duidelijk betere ontwikkeling van de baby. In deze studie kregen zwangere vrouwen vanaf week 24 vijf keer in de week een supplement met 300 mg
DHA of een placebo met maïsolie. Zij met het DHA supplement bleken duidelijk minder symptomen te krijgen van een depressie. De meeste zwangere vrouwen eten trouwens doorgaans slechts 50-70 mg
DHA per dag, terwijl 200 mg geadviseerd wordt.
Omega-3 Consumed During Pregnancy Curbs Risk for Postpartum Depression Symptoms
Fish has long been considered in myriad cultures to be "brain food," but only recently has bona fide science begun to support this deep-rooted belief. Researchers now know that the omega-3 fatty acids found in oily fish such as salmon and herring may play a critical role in both development and maintenance of the brain and nerves. Although sufficient amounts of these long-chain fats can be synthesized endogenously by most adults, experts recommend that pregnant women and infants get additional amounts of these compounds from their diets.
This, combined with research suggesting that these fats play a critical role in cognitive and visual development during early life, has prompted much research and product development aimed at pregnant women and newborn infants. Studies have also suggested that higher consumption of certain omega-3 fatty acids may also benefit adult mental health as well -- for instance, as it might relate to lower risk for depression.
Dr. Michelle Price Judge, a faculty member at the University of Connecticut School of Nursing, is keenly interested in how omega-3 fatty acids consumed during pregnancy impact both maternal and infant health. She has demonstrated previously that maternal consumption of docosahexaenoic acid (DHA; a prominent omega-3 fatty acid) during pregnancy gives infants a developmental advantage even 9 months after they are born. These findings prompted her to consider the benefits that DHA could holistically have on the maternal-infant dyad. Specifically, might greater omega-3 fatty acid intake during pregnancy lower risk for postpartum depression, a condition that leads to a multitude of problems including interruptions in maternal-infant attachment and subsequent impairments in later infant development?
As part of the scientific program of the American Society for Nutrition, results from this study will be presented at the Experimental Biology 2011 meeting in Washington, DC.
To answer this question, Dr. Judge oversaw a randomized, double-blind, placebo-controlled dietary intervention trial in which 52 pregnant women took either a placebo (corn oil) or a fish oil capsule containing 300 milligrams of DHA 5 days each week from 24-40 weeks of pregnancy. This is the amount a woman would consume if she ate about ½ serving of salmon. It is noteworthy that dietary DHA intake during pregnancy has been estimated to be 50-70 milligrams of DHA daily: a mere fraction of the 200 milligrams daily that is considered optimal during pregnancy by most experts. Using the Postpartum Depression Screening Scale developed by her colleague and coauthor Dr. Cheryl Beck, Judge was able to categorize postpartum women as having negligible depressive symptoms, significant symptoms of postpartum depression, or being "positive" for this condition. The Postpartum Depression Screening Scale also assisted the research team in discerning between several symptoms specific to the disorder including sleeping/eating disturbances, anxiety, emotional liability, confusion, loss of self, guilt, and thoughts of suicide.
Although the study did not have enough women to investigate if fish oil consumption resulted in a lower incidence of diagnosable postpartum depression, women in the treatment group had significantly lower total Postpartum Depression Screening Scale scores, with significantly fewer symptoms common to postpartum depression. For example, compared to those in the control group, women in the fish oil group were less likely to report symptoms related to anxiety and loss of self.
Judge and coworkers concluded "DHA consumption during pregnancy -- at levels that are reasonably attained from foods -- has the potential to decrease symptoms of postpartum depression." Why is this important? For starters, some experts estimate that postpartum depression affects a whopping 25% of new mothers. And healthcare providers agree that this condition can have devastating consequences, not only for the women experiencing it but also for their children and family.
The bottom line? Although larger-scale intervention studies will be needed to better understand the mechanisms and magnitude by which fish oil consumption can improve postpartum mental health, women would be wise to eat at least a serving of high-omega-3 fish 2-3 days per week. Although fish oil supplements may be more acceptable to some women, the real thing is clearly the more nutritious option as a serving of fish is also protein- and mineral-rich. Clearly, fish as a "brain food" is gaining the nod from not only from the general public, but scientists as well.
Dr. Michelle Price Judge (University of Connecticut), Dr. Cheryl Beck (University of Connecticut), Dr. Holiday Durham (Louisiana State University), Michele Mckelvey (University of Connecticut), and Dr. Carol Lammi-Keefe (Louisiana State University) were coauthors on this paper.
This study was funded by the Patrick and Catherine Weldon Donaghue Medical Research Foundation.
(Augustus 2011)
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