Omega-3 vetzuren tegen tandvleesontstekingen*
Uit een Australisch onderzoek onder eerdere studies blijkt dat voeding rijk aan
omega-3 vetzuren een goede behandeling is tegen
tandvleesontstekingen en
parodontitis. Twee keer per week vette vis eten zorgt voor duidelijk minder ontstekingen en daardoor minder parodontitis.
Fish oil supplementation as adjunct therapy for periodontitis
Alison Coates1, Mark Bartold2, Toby Hughes2 and Peter Howe1
1 Nutritional Physiology Research Centre, School of Health Sciences, University of South Australia, Adelaide, Australia
2 School of Dentistry, University of Adelaide, Adelaide, Australia
Long chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA) found in fish oil have anti-inflammatory properties that may benefit periodontal health.
The present study reviewed evidence for the use of fish oil supplementation as adjunct therapy for periodontitis. Medline, Embase, Scopus and Cochrane databases were searched using the terms ‘omega-3' or ‘n-3 PUFA’ and ‘periodontal disease’ or ‘periodontitis’. Articles were included if they were original studies, involved humans, written in English and published before November 1 2011.
Ten unique studies were identified, but two were excluded as they did not feature periodontitis. In one retrospective and three cross-sectional studies, the prevalence of periodontitis was inversely associated with dietary intakes of LCn-3 PUFA. Four clinical trials were identified with low participant numbers (n=30–80), LC n-3 PUFA doses ranging from 900 – 3000 mg / day and supplementation lasting eight days to six months. Only one study included a measure of adherence to supplementation. Improvements in clinical measures tended to occur in all studies, but were significant only in two that used a combination of fish oil and aspirin.
Fish oil supplementation shows promise as an adjunct therapy for periodontitis. Long term clinical trials that include biomarkers of compliance are critical for interpreting clinical outcomes. There was no funding source for this
study. (Mei 2012)
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