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Veel fructose geeft hogere kans op metabool syndroom*
Uit een Iraanse studie onder ruim 2.500 personen in de leeftijd van 19-70 jaar blijkt dat voeding rijk aan fructose de kans op het metabool syndroom sterk doet toenemen. Zij met de hoogste inname van fructose bleken bij de mannen en de vrouwen resp. 33 en 20% meer kans te geven op dit syndroom. Zo bleek ook een hogere kans op overgewicht (vooral in de buik) met resp. 39 en 20%, hogere kans op hoge bloeddruk met resp. 11 en 9% en de hogere kans op hogere bloedsuikerwaarden met 9%. De hoeveelheid fructose in de voeding is de laatste honderd jaar verviervoudigd vooral door de toevoeging van fructosesiroop aan kant en klare voeding en frisdranken.
Dietary fructose and risk of metabolic syndrome in adults: Tehran Lipid and Glucose study
Firoozeh Hosseini-Esfahani1, Zahra Bahadoran1, Parvin Mirmiran2*, Somayeh Hosseinpour-Niazi 1, Farhad Hosseinpanah1 and Fereidoun Azizi3 
· * Corresponding author: Parvin Mirmiran mirmiran@endocrine.ac.ir 
Nutrition & Metabolism 2011, 8:50 doi:10.1186/1743-7075-8-50
Abstract
Background
Studies have shown that the excessive fructose intake may induce adverse metabolic effects. There is no direct evidence from epidemiological studies to clarify the association between usual amounts of fructose intake and the metabolic syndrome. 
Objective
The aim this study was to determine the association of fructose intake and prevalence of metabolic syndrome (MetS) and its components in Tehranian adults. 
Methods
This cross-sectional population based study was conducted on 2537 subjects (45% men) aged 19-70 y, participants of the Tehran Lipid and Glucose Study (2006-2008). Dietary data were collected using a validated 168 item semi-quantitative food frequency questionnaire. Dietary fructose intake was calculated by sum of natural fructose (NF) in fruits and vegetables and added fructose (AF) in commercial foods. MetS was defined according to the modified NCEP ATP III for Iranian adults. 
Results
The mean ages of men and women were 40.5 ± 13.6 and 38.6 ± 12.8 years, respectively. Mean total dietary fructose intakes were 46.5 ± 24.5 (NF: 19.6 ± 10.7 and AF: 26.9 ± 13.9) and 37.3 ± 24.2 g/d (NF: 18.6 ± 10.5 and AF: 18.7 ± 13.6) in men and women, respectively. Compared with those in the lowest quartile of fructose intakes, men and women in the highest quartile, respectively, had 33% (95% CI, 1.15-1.47) and 20% (95% CI, 1.09-1.27) higher risk of the metabolic syndrome; 39% (CI, 1.16-1.63) and 20% (CI, 1.07-1.27) higher risk of abdominal obesity; 11% (CI, 1.02-1.17) and 9% (CI, 1.02-1.14) higher risk of hypertension; and 9% (CI, 1-1.15) and 9% (1.04-1.12) higher risk of impaired fasting glucose. 
Conclusion
Higher consumption of dietary fructose may have adverse metabolic effects.
Het volledige artikel.
(December 2011) 

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