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Smaakversterker zorgt voor metaboolsyndroom*
Uit een studie onder 349 Thaise vrouwen blijkt dat voeding rijk aan de smaakversterker MSG de kans op het metaboolsyndroom en overgewicht duidelijk doet toenemen. MSG, Mononatriumglutamaat (het mono-natriumzout van glutaminezuur), is een smaakversterker die toegepast wordt in vele hartige voedingsmiddelen en bijv. het keukenkruid ve-tsin. Het is een additief en heeft E-nummer 621.
Monosodium glutamate (MSG) intake is associated with the prevalence of metabolic syndrome in a rural Thai population
Tonkla Insawang, Carlo Selmi, Ubon Cha'on, Supattra Pethlert, Puangrat Yongvanit, Premjai Areejitranusorn, Patcharee Boonsiri, Tueanjit Khampitak, Roongpet Tangrassameeprasert, Chadamas Pinitsoontorn, Vitoon Prasongwattana, M Eric Gershwin and Bruce D Hammock 
Nutrition & Metabolism 2012, 9:50 doi:10.1186/1743-7075-9-50
Abstract (provisional)
Background
Epidemiology and animal models suggest that dietary monosodium glutamate (MSG) may contribute to the onset of obesity and the metabolic syndrome. 
Methods
Families (n = 324) from a rural area of Thailand were selected and provided MSG as the sole source for the use in meal preparation for 10 days. Three hundred forty-nine subjects aged 35-55 years completed the study and were evaluated for energy and nutrient intake, physical activity, and tobacco smoking. The prevalence of overweight and obesity (BMI [greater than or equal to] 25 kg/m2), insulin resistance (HOMA-IR >3), and the metabolic syndrome (ATP III criteria) were evaluated according to the daily MSG intake. 
Results
The prevalence of the metabolic syndrome was significantly higher in the tertile with the highest MSG intake. Further, every 1 g increase in MSG intake significantly increased the risk of having the metabolic syndrome (odds ratio 1.14, 95% confidence interval-CI- 1.12 - 1.28) or being overweight (odds ratio 1.16, 95% CI 1.04 - 1.29), independent of the total energy intake and the level of physical activity. 
Conclusion
Higher amounts of individual MSG consumption are associated with the risk of having the metabolic syndrome and being overweight independent of other major determinants. 
De volledige studie. (September 2012)

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