Peterselie tegen groei borstkanker*
Uit een studie weliswaar met ratten blijkt dat bioactieve stoffen in peterselie de groei van
borstkankercellen kunnen doen stoppen. De bioactieve stof
apigenine in peterselie zorgde dat in de tumoren van de ratten minder nieuwe bloedvaatjes gemaakt werden, zodat de tumoren niet meer de voedingsstoffen kregen om te kunnen groeien. De ratten die behandeld werden met apigenine hadden dan ook duidelijk minder en
kleinere tumoren in vergelijking met de ratten zonder apigenine. Het ontstaan van kankercellen kon apigenine niet voorkomen. Het is nog onduidelijk hoeveel apigenine mensen moeten innemen om het effect te bewerkstelligen zeggen de onderzoekers "Het lijkt goed om in ieder geval een kleine hoeveelheid apigenine in het bloed te hebben om kanker te vertragen." De volgende fase van het onderzoek is het bestuderen van het effect op mensen.
Parsley component can stop breast cancer cells from growing: Study
A compound in parsley, celery and other plant products, including fruits and nuts, can stop certain breast cancer tumour cells from multiplying and growing, reveals a study by Salman Hyder, professor of biomedical sciences in College of Veterinary Medicine and Dalton Cardiovascular Research Centre, University of Missouri. Parsley is usually used as a decorative accent to a scrumptious
meal.
In his study, Salman Hyder exposed rats with a certain type of breast cancer to apigenin, a common compound found in parsley, celery and other plant products. The rats that were exposed to the apigenin developed fewer tumours and experienced significant delays in tumour formation compared to those rats that were not exposed to apigenin. Hyder believes this finding could impact women who are taking certain hormone replacement
therapies.
“Six to 10 million women in the United States receive hormone replacement therapy (HRT),” says Salman Hyder. “We know that certain synthetic hormones used in HRT accelerate breast tumour development. In our study, we exposed the rats to one of the chemicals used in the most common HRTs received in the United States – a progestin called medroxyprogesterone acetate (MPA) – which also happens to be the same synthetic hormone that accelerates breast tumour development.”
When tumour cells develop in the breast in response to MPA, they encourage new blood vessels to form within tumours. The blood vessels then supply needed nutrients for the tumours to grow and multiply. Salman Hyder found that apigenin blocked new blood vessel formation, thereby delaying, and sometimes stopping, the development of the tumours. Hyder also found that the compound reduced the overall number of tumours. However, while apigenin did delay tumour growth, it did not stop the initial formation of cancer cells within the breast.
Apigenin is most prevalent in parsley and celery, but can also be found in apples, oranges, nuts and other plant products. However, apigenin is not absorbed efficiently into the bloodstream, so scientists are unsure of how much can or should be
ingested.
“We don’t have specific dosage for humans yet,” says Salman Hyder. “However, it appears that keeping a minimal level of apigenin in the bloodstream is important to delay the onset of breast cancer that progresses in response to progestins such as MPA. It’s probably a good idea to eat a little parsley and some fruit every day to ensure the minimal amount. However, you can also find this compound in pill supplements in the health food section of many stores. Of course, you should always check with your doctor before making any major changes to your diet or
lifestyle.”
The next phrase of studies should include human clinical trials to determine the appropriate dosage amount, says Salman Hyder. He believes further study on humans is necessary to address any health and safety issues that might
exist. (Mei 2011)
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