Oerdieet nog gezonder dan mediterraan dieet*
Uit een kleine studie onder 29 hartpatiënten, met glucose intolerantie en een buikomtrek van meer dan 94 cm, blijkt dat een
oerdieet nog gezonder is dan een mediterraan
dieet. 12 weken lang kreeg de helft van de deelnemers een oerdieet of een mediterraan dieet. Na afloop bleek een oerdieet een duidelijke verbetering te geven op de glucose tolerantie, en zorgde ook voor duidelijk minder calorie-inname (1.400 Kcal tegenover 1.850 Kcal bij het mediterraan dieet), de deelnemers voelden zich eerder verzadigd. De gewichtsafname was vergelijkbaar 5 kg (oerdieet) tegen 3,8 kg, bijna 6 cm minder buikomtrek tegen 3 cm bij een mediterraan dieet.
A paleolithic diet is more satiating per calorie than a mediterranean-like diet in individuals with ischemic heart disease
Tommy Jönsson1 , Yvonne Granfeldt2 , Charlotte Erlanson-Albertsson3 , Bo Ahrén1 and Staffan Lindeberg1
1 Department of Clinical Science, B11 BMC, University of Lund, SE-221 84 Lund, Sweden
2 Department of Food Technology, Engineering and Nutrition, University of Lund, Lund, Sweden
3 Section of Metabolism, Endocrinology and Diabetes, Department of Experimental Medicine, University of Lund, Lund, Sweden
author email corresponding author email
Nutrition & Metabolism 2010, 7:85doi:10.1186/1743-7075-7-85
Abstract
Background
We found marked improvement of glucose tolerance and lower dietary energy intake in ischemic heart disease (IHD) patients after advice to follow a Paleolithic diet, as compared to a Mediterranean-like diet. We now report findings on subjective ratings of satiety at meals and data on the satiety hormone leptin and the soluble leptin receptor from the same study.
Methods
Twenty-nine male IHD patients with impaired glucose tolerance or diabetes type 2, and waist circumference > 94 cm, were randomized to ad libitum consumption of a Paleolithic diet (n = 14) based on lean meat, fish, fruit, vegetables, root vegetables, eggs, and nuts, or a Mediterranean-like diet (n = 15) based on whole grains, low-fat dairy products, vegetables, fruit, fish, and oils and margarines during 12 weeks. In parallel with a four day weighed food record the participants recorded their subjective rating of satiety. Satiety Quotients were calculated, as the intra-meal quotient of change in satiety during meal and consumed energy or weight of food and drink for that specific meal. Leptin and leptin receptor was measured at baseline and after 6 and 12 weeks. Free leptin index was calculated as the ratio leptin/leptin receptor.
Results
The Paleolithic group were as satiated as the Mediterranean group but consumed less energy per day (5.8 MJ/day vs. 7.6 MJ/day, Paleolithic vs. Mediterranean, p = 0.04). Consequently, the quotients of mean change in satiety during meal and mean consumed energy from food and drink were higher in the Paleolithic group (p = 0.03). Also, there was a strong trend for greater Satiety Quotient for energy in the Paleolithic group (p = 0.057). Leptin decreased by 31% in the Paleolithic group and by 18% in the Mediterranean group with a trend for greater relative decrease of leptin in the Paleolithic group. Relative changes in leptin and changes in weight and waist circumference correlated significantly in the Paleolithic group (p < 0.001) but not in the Mediterranean group. Changes in leptin receptor and free leptin index were not significant.
Conclusions
A Paleolithic diet is more satiating per calorie than a Mediterranean-like
diet.
Trial registration
ClinicalTrials.gov NCT00419497 (Februari 2011)
Reacties:
