Magnesium tegen ontstekingen*
Uit een studie onder 3.713 postmenopauzale vrouwen blijkt dat magnesium wel eens een goede
ontstekingsremmer kan zijn, zonder bijwerkingen. 100 mg magnesium per dag doet de hoeveelheid onstekingsmarkers als CRP (C-reactief proteïne), TNFa (Tumornecrosefactor-alfa) en IL6 (Interleukine-6) duidelijk afnemen. Ook ontstekingen in de bloedvaten nemen met magnesium duidelijk af zodat plaquevorming in de bloedvaten voorkomen kan worden.
Fight and prevent inflammation naturally with magnesium
While magnesium has always been known to be a very powerful mineral, a study involving 3,713 postmenopausal women has fully shown it's anti-inflammatory effects. With 100 mg of magnesium per day, anti-inflammatory properties were experienced. Magnesium could be of great aid to those who wish to avoid the horrible side effects of anti-inflammatory pharmaceuticals.
According to the study, inflammatory indicators such as CRP (C-reactive protein), TNFa (tumor necrosis factor alpha), and IL6 (interleukin 6) were all reduced when magnesium intake was increased. This means that magnesium plays a direct role in lowering common inflammatory markers, further showing it's beneficial properties.
Inflammation regarding the walls of the arteries was also reduced in response to an increased intake of magnesium. What this means is with increased intake of magnesium, it is much harder for plaque to form on the lining of the arteries. Since plaque forms due to the inflammation of the arterial lining, this is great news.
With the soil's nutrients being stripped, magnesium is becoming a rather scarce mineral within our crops. Coupled with an unhealthy diet revolving around mostly processed foods, it's easy to see why many of us are magnesium-deficient. Quality fruits and vegetables contain the mineral, but a shocking amount of people do not eat an adequate amount of fruits and vegetables (if any).
Inflammation has been tied to countless medical conditions, causing millions to suffer each day. Using magnesium to aid in the fight against inflammation is a wise decision, and one that requires no pharmaceuticals.
Sources: Chacko SA, Song Y, Nathan L, Tinker L, de Boer IH, Tylavsky F, Wallace R, Liu S. Relations of dietary magnesium intake to biomarkers of inflammation and endothelial dysfunction in an ethnically diverse cohort of postmenopausal women. Diabetes Care.
Department of Epidemiology, School of Public Health, UCLA, Los Angeles, CA 90095.
Abstract
OBJECTIVE Although magnesium may favorably affect metabolic outcomes, few studies have investigated the role of magnesium intake in systemic inflammation and endothelial dysfunction in humans.
RESEARCH DESIGN AND METHODS Among 3,713 postmenopausal women aged 50-79 years in the Women's Health Initiative Observational Study and free of cardiovascular disease, cancer, and diabetes at baseline, we measured plasma concentrations of high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), turnor necrosis factor-a receptor 2 (TNF-a-R2), soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1 (sVCAM-1), and E-selectin. Magnesium intake was assessed using a semiquantitative food frequency questionnaire.
RESULTS After adjustment for age, ethnicity, clinical center, time of blood draw, smoking, alcohol, physical activity, energy intake, BMI, and diabetes status, magnesium intake was inversely associated with hs-CRP (P for linear trend = 0.003), IL-6 (P < 0.0001), TNF-a-R2 (P = 0.0006), and sVCAM-1 (P = 0.06). Similar findings remained after further adjustment for dietary fiber, fruit, vegetables, folate, and saturated and trans fat intake. Multivariable-adjusted geometric means across increasing quintiles of magnesium intake were 3.08, 2.63, 2.31, 2.53, and 2.16 mg/l for hs-CRP (P = 0.005); 2.91, 2.63, 2.45, 2.27, and 2.26 pg/ml for IL-6 (P = 0.0005); and 707, 681, 673, 671, and 656 ng/ml for sVCAM-1 (P = 0.04). An increase of 100 mg/day magnesium was inversely associated with hs-CRP (-0.23 mg/l ± 0.07; P = 0.002), IL-6 (-0.14 ± 0.05 pg/ml; P = 0.004), TNF-a-R2 (-0.04 ± 0.02 pg/ml; P = 0.06), and sVCAM-1 (-0.04 ± 0.02 ng/ml; P = 0.07). No significant ethnic differences were observed.
CONCLUSIONS High magnesium intake is associated with lower concentrations of certain markers of systemic inflammation and endothelial dysfunction in postmenopausal
women. (Januari 2011)
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