Glycine tegen en bij artrose.*
Uit een Spaans onderzoek onder 600 mensen van 4-85 jaar blijkt dat het aminozuur glycine
artrose kan voorkomen en symptomen duidelijk kan
verminderen. Glycine is een niet-essentieel aminozuur dat door het lichaam gebruikt wordt om
proteïne (eiwitten) aan te maken en dat voorkomt in vis, vlees en melkproducten.
De gebruikte dagelijkse dosis glycine bedroeg 10 gram: 5 gram 's morgens en 5 gram 's avonds.
De glycine zorgt voor een algemene verlichting van de pijn die door de artrose veroorzaakt wordt. Dit gebeurt in de meeste gevallen tussen twee weken en vier maanden. Een opmerkelijk resultaat en dat zonder extra medicatie.
Een duidelijke verklaring hebben de onderzoekers niet gevonden, maar het lijkt duidelijk dat de stofwisseling slechts in staat is om een zeer beperkte hoeveelheid glycine aan te maken.
Daarom stellen de wetenschappers voor om dit aminozuur toe te voegen aan de
groep essentiële aminozuren.
Glycine Supplement Helps Prevent Degenerative Diseases Such As Arthrosis Or Osteoporosis
Glycine is a non-essential amino acid used by an organism to synthesise proteins and is present in foods such as fish, meat or dairy products. The study, carried out at the Cellular Metabolism Institute in Tenerife and at the Department of Biochemistry and Molecular Biology of the University of Granada , established that the direct intake of this substance as a food additive helps to prevent arthrosis and other degenerative diseases, in addition to other diseases related to a weakness in the mechanical structure of the organism, including the difficulty of repairing physical
injuries.
The work of De Paz Lugo was developed at the Cellular Metabolism Institute (CMI) in Tenerife, where researchers studied the effect of the glycine supplement on the diet of a group of 600 volunteers affected by different diseases related to the mechanical structure of the organism such as arthrosis, physical injuries or osteoporosis. The patients analysed were aged 4-85, and the average age was 45.
In all cases, there was a notable improvement in the symptomology. "Thefore -- according to De Paz Lugo -- we concluded that many degenerative diseases such as arthrosis can be treated as deficiency diseases due to the lack of glycine, since supplementing a diet with this amino acid leads to a notable improvement in symptomology without the need to take
pain-killers."
A very common disease
Arthrosis is the most common osteoarticulary problem in our society: more than 50% of the population suffer from it after the age of 65, and 80% of people over 75. It consists of a degeneration of the articulary cartilage which disappears until it leaves the subchondral bone exposed. Arthrosis has no cure at present and the most widely used treatments are pain-killers and NSAID (non-steroidal antiinflammatory drugs), which only relieve pain but do not repair the damage in the cartilage or influence the development of the
disease.
The work carried out by the scientist from the CMI shows that collagen has a unique structure with a right-handed triple superhelix in which the glycine represents a third of its residues. Mathematical analysis of the metabolic route of the synthesis of the glycine, developed by the research group to which Patricia de Paz belongs, demonstrated that this amino acid should be considered an essential amino acid.
The doctoral thesis carried out at the CMI and the UGR has shown that the capacity of the metabolism to synthesise glycine is very limited. The conclusion of this study is that glycine, administered in daily doses of 10 grams divided into two doses of 5 grams "one in the morning and one at night" leads to a general improvement in these problems over a period of time which, in most cases, is between two weeks and four
months.
Reference:
Dr. Patricia de Paz Lugo. Cellular Metabolism Institute, La Laguna (Tenerife).
Source: Dr. Patricia de Paz Lugo
Universidad de Granada (September 2007)
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