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Pruimen tegen osteoporose*
Uit een kleine studie onder honderd postmenopauzale vrouwen blijkt dat het regelmatig eten van gedroogde pruimen het proces van botontkalking duidelijk kan verminderen. De eerste jaren na de menopauze staan bekend om een sterk verhoogde kans op botontkalking als gevolg van lage oestrogeen spiegels. In de studie kregen 55 vrouwen een jaar lang dagelijks 100 gram gedroogde pruimen (ca. 10 stuks) en 45 vrouwen eenzelfde portie gedroogde appels. Na 1 jaar bleken de vrouwen in de pruimengroep een duidelijk betere botdichtheid te hebben dan de vrouwen in de appelgroep. 
No Bones About It: Eating Dried Plums Helps Prevent Fractures and Osteoporosis, Study Suggests
When it comes to improving bone health in postmenopausal women -- and people of all ages, actually -- a Florida State University researcher has found a simple, proactive solution to help prevent fractures and osteoporosis: eating dried plums.
"Over my career, I have tested numerous fruits, including figs, dates, strawberries and raisins, and none of them come anywhere close to having the effect on bone density that dried plums, or prunes, have," said Bahram H. Arjmandi, Florida State's Margaret A. Sitton Professor and chairman of the Department of Nutrition, Food and Exercise Sciences in the College of Human Sciences. "All fruits and vegetables have a positive effect on nutrition, but in terms of bone health, this particular food is exceptional."
Arjmandi and a group of researchers from Florida State and Oklahoma State University tested two groups of postmenopausal women. Over a 12-month period, the first group, consisting of 55 women, was instructed to consume 100 grams of dried plums (about 10 prunes) each day, while the second -- a comparative control group of 45 women -- was told to consume 100 grams of dried apples. All of the study's participants also received daily doses of calcium (500 milligrams) and vitamin D (400 international units).
The group that consumed dried plums had significantly higher bone mineral density in the ulna (one of two long bones in the forearm) and spine, in comparison with the group that ate dried apples. This, according to Arjmandi, was due in part to the ability of dried plums to suppress the rate of bone resorption, or the breakdown of bone, which tends to exceed the rate of new bone growth as people age.
The group's research, was published in the British Journal of Nutrition. Arjmandi conducted the research with his graduate students Shirin Hooshmand, Sheau C. Chai and Raz L. Saadat of the College of Human Sciences; Dr. Kenneth Brummel-Smith, Florida State's Charlotte Edwards Maguire Professor and chairman of the Department of Geriatrics in the College of Medicine; and Oklahoma State University statistics Professor Mark E. Payton.
In the United States, about 8 million women have osteoporosis because of the sudden cessation of ovarian hormone production at the onset of menopause. What's more, about 2 million men also have osteoporosis.
"In the first five to seven postmenopausal years, women are at risk of losing bone at a rate of 3 to 5 percent per year," Arjmandi said. "However, osteoporosis is not exclusive to women and, indeed, around the age of 65, men start losing bone with the same rapidity as women."
Arjmandi encourages people who are interested in maintaining or improving their bone health to take note of the extraordinarily positive effect that dried plums have on bone density.
"Don't wait until you get a fracture or you are diagnosed with osteoporosis and have to have prescribed medicine," Arjmandi said. "Do something meaningful and practical beforehand. People could start eating two to three dried plums per day and increase gradually to perhaps six to 10 per day. Prunes can be eaten in all forms and can be included in a variety of recipes."
The U.S. Department of Agriculture funded Arjmandi's research. The California Dried Plum Board provided the dried plums for the study, as well as some funding to measure markers of oxidative stress. (Augustus 2011) 

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