Drie weken een vegetarisch dieet voor een goede gezondheid*
Uit een kleine studie onder 43 personen blijkt dat drie weken een streng vegetarisch dieet zorgt voor goede biomarkers, een sterk verhoogde
antioxidatieve kracht en duidelijk minder oxidatieve stress in het lichaam. Het is ook nog eens goed voor het gewicht want de calorie-inname daalde van 2.200 naar 1.700 per dag.
A 21 day Daniel Fast improves selected biomarkers of antioxidant status and oxidative stress in men and women
Richard J Bloomer*, Mohammad M Kabir, John F Trepanowski, Robert E Canale and Tyler M Farney
· * Corresponding author: Richard J Bloomer rbloomer@memphis.edu
Author Affiliations
Cardiorespiratory/Metabolic Laboratory The University of Memphis Memphis, TN 38152, USA
Nutrition & Metabolism 2011, 8:17 doi:10.1186/1743-7075-8-17
© 2011 Bloomer et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background
Dietary modification via both caloric and nutrient restriction is associated with multiple health benefits, some of which are related to an improvement in antioxidant status and a decrease in the production of reactive oxygen species. The Daniel Fast is based on the Biblical book of Daniel, is commonly partaken for 21 days, and involves food intake in accordance with a stringent vegan diet. The purpose of the present study was to determine the effect of a 21 day Daniel Fast on biomarkers of antioxidant status and oxidative stress.
Methods
43 subjects (13 men; 30 women; 35 ± 1 yrs; range: 20-62 yrs) completed a 21 day Daniel Fast following the guidelines provided by investigators. Subjects reported to the lab in a 12 hour post-absorptive state both pre fast (day 1) and post fast (day 22). At each visit, blood was collected for determination of malondialdehyde (MDA), hydrogen peroxide (H2O2), nitrate/nitrite (NOx), Trolox Equivalent Antioxidant Capacity (TEAC), and Oxygen Radical Absorbance Capacity (ORAC). Subjects recorded dietary intake during the 7 day period immediately prior to the fast and during the final 7 days of the fast.
Results
A decrease was noted in MDA (0.66 ± 0.0.03 vs. 0.56 ± 0.02 μmol L-1; p = 0.004), while H2O2 demonstrated a trend for lowering (4.42 ± 0.32 vs. 3.78 ± 0.21 μmol L-1; p = 0.074). Both NOx (18.79 ± 1.92 vs. 26.97 ± 2.40 μmol L-1; p = 0.003) and TEAC (0.47 ± 0.01 vs. 0.51 ± 0.01 mmol L-1; p = 0.001) increased from pre to post fast, while ORAC was unchanged (5243 ± 103 vs. 5249 ± 183 μmol L-1 TE; p = 0.974). As expected, multiple differences in dietary intake were noted (p < 0.05), including a reduction in total calorie intake (2185 ± 94 vs. 1722 ± 85).
Conclusion
Modification of dietary intake in accordance with the Daniel Fast is associated with an improvement in selected biomarkers of antioxidant status and oxidative stress, including metabolites of nitric oxide (i.e., NOx).
Het
volledige artikel. (Juli 2011)
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