Vitamine D tijdens de zwangerschap*
Uit een Canadese studie blijkt dat vitamine D tijdens de
zwangerschap niet alleen goed is voor moeder en baby doch ook veilig genomen kan worden. Recente studies hebben laten zien dat voldoende vitamine D tijdens de zwangerschap heel belangrijk is. In deze studie kregen een kleine 500 vrouwen met een zwangerschap van 12-16 weken dagelijks tot aan de bevalling of 10 of 50 of 100 mcg vitamine D. Maandelijks werden de vrouwen gecontroleerd en bij niemand werd enige bijwerking vastgesteld. Wel werden duidelijk minder voorweeën, te vroege geboortes en ontstekingen vastgesteld vooral in de groep met de hoogste dosering vitamine D.
Taking vitamin D supplements during pregnancy safe for mother, baby: Study
Taking vitamin D supplements during pregnancy is not only safe for mother and baby, but also can prevent preterm labor/births and infections, according to results of a randomized controlled study to be presented at the Pediatric Academic Societies (PAS) annual meeting in Vancouver, British Columbia, Canada.
In the 1950s and '60s, people were concerned that vitamin D could cause birth defects, according to Carol L. Wagner, MD, lead author of the study and a pediatric researcher at Medical University of South Carolina. It now is known that vitamin D is important for maternal and infant health, including bone health and immune function.
Recent studies have shown that vitamin D deficiency during pregnancy is a serious public health issue.
"Diet doesn't provide enough vitamin D, and we don't go in the sun as much as we need," Dr. Wagner said.
Therefore, she and her colleagues, including Bruce W. Hollis, PhD, who has worked in the field of vitamin D research for the last 30 years, set out to determine the optimal dose of vitamin D supplements for pregnant women without doing harm.
Researchers randomized 494 pregnant women at 12-16 weeks' gestation into three treatment groups. Group one received 400 International Units (IU) of vitamin D a day until delivery; group two received 2,000 IU and group three received 4,000 IU. The women were evaluated monthly to ensure safety.
"No adverse events related to vitamin D dosing were found in any of the three arms of the study," Dr. Wagner said.
Investigators also looked at the effects of vitamin D supplementation on complications during pregnancy, including preeclampsia, gestational diabetes, infections, and preterm labor and birth.
"The spectacular part of the study was it showed women replete in vitamin D had lower rates of preterm labor and preterm birth, and lower rates of infection," Dr. Wagner said.
The greatest effects were seen among women taking 4,000 IU of vitamin D per day. Therefore, the researchers recommend this daily regimen for all pregnant women.
Dr. Wagner will discuss the two parts of the study in separate presentations. Source: American Academy of Pediatrics (Juli 2010)
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