Vitamine D belangrijk voor vrouwen in verwachting.*
Volgens de Belgische professor Chantal Mathieu tijdens een congres in Birmingham is voldoende vitamine D voor een vrouw in verwachting heel belangrijk. Dit stimuleert het immuunsysteem en dat is goed voor zowel de vrouw zelf als voor het ongeboren kind. Vrouwen in verwachting kunnen makkelijk een tekort krijgen aan vitamine D en daardoor zelf maar nog meer het ongeboren kind blootstellen aan autoimmuunziektes zoals diabetes of schildklierproblemen. Regelmatig, met verstand, in de zon geeft al veel vitamine D. Zonodig aan te vullen met supplementen.
Een andere Amerikaanse studie laat zien dat de meeste zwangere vrouwen zelfs zij die regelmatig supplementen nemen te weinig Vitamine D in hun lichaam hebben. Behalve zon, supplementen is voeding rijk aan vitamine D is voor iedere zwangere vrouw heel belangrijk vooral als de zwangerschap plaatsvindt in de herfst en winter.
Pregnant
Women 'Should Supplement Vitamin D'
Pregnant
women should take steps to ensure they have adequate vitamin D in their diet, or
they and especially their unborn children may run the risk of developing
autoimmune diseases such as diabetes and thyroid diseases.
Speaking at the British Endocrine Societies meeting in Birmingham, Dr Chantal
Mathieu (University of Leuven, Belgium) said that research had shown that low
levels of vitamin D are associated with autoimmune diseases. This is
particularly important during pregnancy, when the nutritional requirement of the
developing baby means that mothers can easily develop shortages of vitamin D.
In recent work Dr Mathieu has shown that giving vitamin D to mice who would
normally develop type 1 diabetes has helped protect them against the onset of
the disease.
Vitamin D deficiency is associated with poor bone health and rickets, but much
recent work has shown that people with vitamin D deficiency tend to have a poor
immune system, and take longer to recover from infections.
Dr Mathieu said
There is now a lot of work showing that vitamin D deficiency is associated with
a poor immune system. This makes it difficult to recover from infection, but it
also seems to make you more likely to develop autoimmune diseases. Recently we
have been able to prevent the development of type 1 diabetes in mice with a
predisposition to develop the disease.
Pregnant mothers are particularly liable to develop vitamin D deficiency, and so
they are at increased risk of developing autoimmune diseases through being
pregnant.
There are two ways of ensuring you have enough vitamin D. You can make sure that
you get an adequate amount of sunshine bearing in mind that this has to be done
sensibly, because too much sunshine can cause problems such as skin cancer. Or
it might be easier simply to take vitamin supplements during pregnancy.
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Vitamin
D Deficiency Widespread During Pregnancy
Even
regular use of prenatal multivitamin supplements is not adequate to prevent
vitamin D insufficiency, University of Pittsburgh researchers report in the
current issue of the Journal of Nutrition, the publication of the
American Society for Nutrition. A condition linked to rickets and other
musculoskeletal and health complications, vitamin D insufficiency was found to
be widespread among women during pregnancy, particularly in the northern
latitudes.
"In our study, more than 80 percent of African-American women and nearly
half of white women tested at delivery had levels of vitamin D that were too low,
even though more than 90 percent of them used prenatal vitamins during pregnancy,"
said Lisa Bodnar, Ph.D., M.P.H., R.D., assistant professor of epidemiology at
the University of Pittsburgh Graduate School of Public Health (GSPH) and lead
author of the study. "The numbers also were striking for their newborns -
92.4 percent of African-American babies and 66.1 percent of white infants were
found to have insufficient vitamin D at birth."
A vitamin closely associated with bone health, vitamin D deficiency early in
life is associated with rickets - a disorder characterized by soft bones and
thought to have been eradicated in the United States more than 50 years ago - as
well as increased risk for type 1 diabetes, asthma and schizophrenia.
"A newborn's vitamin D stores are completely reliant on vitamin D from the
mother," observed Dr. Bodnar, who also is an assistant investigator at the
university-affiliated Magee-Womens Research Institute (MWRI). "Not
surprisingly, poor maternal vitamin D status during pregnancy is a major risk
factor for infant rickets, which again is becoming a major health problem."
For their study, Dr. Bodnar and her colleagues evaluated data that was collected
on 200 black women and 200 white women who were randomly selected from more than
2,200 women enrolled in the MWRI's Pregnancy Exposures and Preeclampsia
Prevention Study between 1997 and 2001. Samples of maternal blood were collected
prior to 22 weeks pregnancy and again just before delivery, Samples of newborn
umbilical cord blood also were tested for 25 hydroxyvitamin D, an indicator of
vitamin D status. Finding such a proliferation of vitamin D insufficiency in
spite of prenatal multivitamin use is troubling, she noted, suggesting that
higher dosages, differing vitamin formulations or a moderate increase in
sunlight exposure might be necessary to boost vitamin D stores to healthier
levels.
"In both groups, vitamin D concentrations were highest in summer and lowest
in winter and spring," said senior author James M. Roberts, M.D., MWRI
director and professor and vice chair of research in the department of
obstetrics, gynecology and reproductive sciences at the University of Pittsburgh
School of Medicine. "But differences were smaller between seasons for
African-American mothers and babies, whose vitamin D deficiency remained more
constant."
Since vitamin D is made by the body in reaction to sunlight exposure, it has
long been known that vitamin D deficiency is more common among darker-skinned
individuals, particularly in more northern latitudes, where less ultraviolet
radiation reaches the Earth. Indeed, vitamin D deficiency is more than three
times as common in winter than in summer for all women of childbearing age in
the United States. Even so, the Pittsburgh researchers' study is cause for
concern.
"This study is among the largest to examine these questions in this at-risk
population," Marjorie L. McCullough, Sc.D., senior epidemiologist at the
American Cancer Society, wrote in an accompanying editorial. "By the end of
pregnancy, 90 percent of all women were taking prenatal vitamins and yet
deficiency was still common."
Vitamin D is found naturally in fatty fish but few other foods. Primary dietary
sources include fortified foods such as milk and some ready-to-eat cereals and
vitamin supplements. Sun exposure for skin synthesis of vitamin D also remains
critical.
"Our study shows that current vitamin D dietary intake recommendations are
not enough to meet the demands of pregnancy," Dr. Bodnar said. "Improving
vitamin D status has tremendous capacity to benefit public health." (Maart 2007)
(Opm Meer over vitamine D)