Transvetten en
vruchtbaarheid.*
Uit
een onderzoek onder ruim 18.000 vrouwen blijkt dat transvetten de kans op
vruchtbaarheidsproblemen bij vrouwen flink doen toenemen. Vrouwen, waarvan 2%
van hun dagelijkse calorieën uit transvetten bestaat, hebben 70-100% meer kans
op vruchtbaarheidsproblemen als gevolg van het uitblijven van een ovulatie. Bij
een gemiddeld dagelijks inname van 2.000 cal. betekent dat 4 gram transvetten
per dag al voor problemen kan zorgen. 4 gram transvet kan men al binnen krijgen
met het eten van 1 donut of 1 portie patat frites. Volgens de onderzoeksleider
Jorge Chavarro blijkt dat zelfs al kleine hoeveelheden transvetten duidelijke
gevolgen kunnen hebben voor de vruchtbaarheid.
Dietary
fatty acid intakes and the risk of ovulatory infertility 1,2,3
Jorge E Chavarro, Janet W Rich-Edwards, Bernard A Rosner and
Walter C Willett
1 From the Departments of Nutrition (JEC and WCW),
Epidemiology (JEC, JWR-E, and WCW), and Biostatistics (BAR), Harvard School of
Public Health, Boston, MA; and the Department of Ambulatory Care and Prevention
(JWR-E) and the Channing Laboratory, Department of Medicine, Brigham and Women's
Hospital (JWR-E, BAR, and WCW), Harvard Medical School, Boston, MA
Background:Pharmacologic
activation of the peroxisome proliferator–activated receptor gamma
improves ovulatory function in women with polycystic ovary syndrome,
and specific dietary fatty acids can affect PPAR-gamma
activity.
Objective:The
objective of the study was to assess whether the intakes of total
fat, cholesterol, and major types of fatty acids affect the risk of
ovulatory infertility.
Design:We
conducted a prospective cohort study of 18 555 married, premenopausal
women without a history of infertility who attempted a pregnancy or became
pregnant between 1991 and 1999. Diet was assessed twice during
follow-up by using a food-frequency questionnaire.
Results:During
follow-up, 438 incidents of ovulatory infertility were reported. In
logistic regression analyses, intakes of total fat, cholesterol, and
most types of fatty acids were not related to ovulatory infertility.
Each 2% increase in the intake of energy from trans
unsaturated fats, as opposed to that from carbohydrates, was
associated with a 73% greater risk of ovulatory infertility after adjustment for known and
suspected risk factors for this condition [relative risk (RR) = 1.73;
95% CI: 1.09, 2.73]. Obtaining 2% of energy intake from trans
fats rather than from n–6 polyunsaturated fats was associated with
a similar increase in the risk of ovulatory infertility
(RR = 1.79; 95% CI: 1.11, 2.89). In addition, obtaining 2% of energy
from trans fats rather than from monounsaturated fats was
associated with a more than doubled risk of ovulatory infertility (RR = 2.31; 95% CI:
1.09, 4.87).
Conclusion:trans Unsaturated fats may increase the risk of ovulatory infertility when consumed instead of carbohydrates or unsaturated fats commonly found in nonhydrogenated vegetable oils. (Jan. 2007) (Opm. Meer over transvetten)