Vlees, aspirine en borstkanker.*
Uit een Amerikaanse studie onder ruim 600 vrouwen blijkt dat het meer dan 2 keer per maand eten van vlam geroosterd vlees de kans op borstkanker met 74% doet toenemen, tenzij aspirine genomen wordt
Het eten van meer dan 64 gram vlees, ongeacht de manier van bereiden, per dag doet het risico op borstkanker met 43% toenemen.
Het bakken van vlees bij hoge temperaturen boven een open vlam kan leiden tot de vorming van heterocyclische amines, mutagene verbindingen die DNA schade kunnen veroorzaken en daardoor uiteindelijk tot kanker.
Uit de studie bleek ook dat aspirine de schadelijke werking van de heterocyclische amines teniet kan doen.
Researchers from Johns Hopkins University
examined the diets and eating patterns of 312 women with breast cancer and 316
women without the disease, and found that women who ate flame-grilled foods more
than twice per month experienced a 74 percent increased risk of breast cancer
compared to women who never ate flame-grilled foods.
"Cooking meat at high temperatures in
direct heat over an open flame can lead to the production of cancer-causing
chemicals known as heterocyclic amines, or HCAs," said lead researcher Dr.
Kala Visvanathan at a recent conference on cancer prevention sponsored by the
American Association for Cancer Research.
The researchers also reported similar
increases in breast cancer risk for women who ate more meat in general,
Visvanathan said.
Women who reported eating more than 64
grams of meat per day -- compared to women who ate equal to or less than 64
grams per day -- ran a 43 percent increased risk of developing breast cancer,
the researchers found.
The
good news, however, is that taking aspirin negated the potentially harmful
effects.
"We are not certain of the mechanism by which aspirin may be helping
attenuate these risks. This is an area that further study should elucidate as we
search for means to reduce the risk of breast cancer," said Visvanathan.(Nov.
2006)