Cranberry's
voor gezonde tanden.*
Uit onderzoek blijkt dat de vele bioactieve stoffen, zoals favonolen, anthocyanen, tannines en andere fenolen in cranberry's makkelijk de schadelijke effecten van schadelijke bacteriën in de mond kunnen neutraliseren. Die schadelijke bacteriën zorgen voor gaatjes en plaque, een ziekte waarvan bijna iedereen last heeft.
Cranberries
Contain Possible Anti-caries/anti-plaque Agents
Scientists
have discovered that the humble cranberry harbors several anti-oxidants (flavonoids)
that show the ability to counteract the damaging effects of the bacterium
Streptococcus mutans, which causes dental caries (tooth decay). Dental caries is
the most common oral infectious disease that afflicts humans. More than 95% of
all adults have experienced this disease. It is more common than asthma, hay
fever, or chronic bronchitis in 5- to 17-year-old children. The American public
spends close to $40 billion per year to treat this disease or its consequences.
Dental caries results from the interaction of specific bacteria with
constituents of the diet on a susceptible tooth surface. Dental plaque
accumulation is the first clinical evidence of this interaction; dental plaque
is a biofilm which is comprised of a population of bacteria growing on the tooth
surface enmeshed in a polysaccharide matrix. Acid can be formed rapidly by
acidogenic bacteria, such as Streptococcus mutans, within the matrix, and its
persistence results in dissolution of the tooth. Cranberries harbor a plethora
of biological compounds such as flavonoids (e.g., quercetin and myricetin),
phenolic acids (benzoic acid), anthocyanins, condensed tannins, among others.
The researchers have shown that many of these substances can: (i) inhibit
enzymes associated with the formation of the plaque polysaccharide matrix, (ii)
block the adherence of bacteria to surfaces, (iii) prevent acid formation, and (iv)
reduce acid tolerance of cariogenic organisms. The next step in their research
is to identify the specific active constituents in cranberries that could be
useful as anti-caries/anti-plaque agents.
###
This is a summary of abstract #179, "Cranberry Flavonoids on Expression of
Virulence by S. mutans," by H. Koo, S. Gregoire, S. Duarte, J. Sils, A.P.
Singh, and N. Vorsa (University of Rochester School of Medicine and Dentistry,
University of Rochester, NY, USA, and Rutgers University), presented on
Wednesday, June 28, 2006, at the Brisbane Convention & Exhibition Centre,
during the 84th General Session of the International Association for Dental
Research. (
Juli 2006)