Voedingsgewoonte zwangere vrouw hebben levenslange gevolgen voor baby.*
Voorlopige uitkomsten uit een groot Europees project, EARNEST, lijken al aan te geven dat de voeding tijdens de eerste maanden van de zwangerschap van wezenlijk belang is voor de gezondheid van de baby gedurende zijn hele leven. Earnest is een project van 38 onderzoekscentra in 16 landen. Jammer genoeg is het project nog niet zover gevorderd dat al definitieve conclusies en aanbevelingen gedaan kunnen worden.
Pregnancy
Diet Has Lifelong Effects For Baby
University of Nottingham researchers
are targeting Europe's biggest killer diseases - by focusing on the diet of
unborn babies.
Poor nutrition in the womb and in the first months of infancy can condemn an
individual to a life of poor health including higher risks of obesity, diabetes and cardiovascular disease.
Scientists believe a baby is ‘programmed' for a lifetime of good or poor
health in its first few months by the type and amount of nutrition they
receive.
Experts at The University of Nottingham are now heading up part of an £11m
project to pinpoint the best way of giving babies a healthy start that will
benefit them for the whole of their lives.
Their findings will help to shape public policy on mothers' diet in
pregnancy and lactation. The Nottingham team believes the project could have
as big an impact on public health as other lifestyle interventions - such as
decreasing food intake and increasing exercise - which are much more
difficult to impose.
Professor Michael Symonds, Head of the Academic Division of Child Health at
Nottingham University Medical School, said: “What your mother eats and how
you are fed as a baby can programme you for a lifetime of good health or bad
health.
“This obviously has important health implications worldwide, given that we
are living longer, more people are getting cardiovascular disease and we
need to get to grips with the mechanisms behind this.”
The EU-funded project is known as EARNEST, its full title being ‘Early
Nutrition Programming - Long-term follow-up of efficacy and safety trials
and integrated epidemiological, genetic, animal, consumer and economic
research'.
The University of Nottingham team is embarking on a series of intervention
studies, manipulating diet during pregnancy and lactation to establish the
optimum dietary patterns for humans.
Professor Symonds said: “There are two types of baby we should be
particularly concerned about - both the baby that is too small and the baby
that is too large. There has been a 20 per cent increase in birth weight
over the last 10-15 years.
“That is, in part, due to the fact that mothers are larger when they are
getting pregnant and are more likely to suffer from pregnancy diabetes, that
is they are unable to control their blood glucose adequately.
“The result of that is the baby will actually be larger at birth… which
could well be one factor that is contributing to later obesity. If you start
off being too large at birth, then you are on a track to remain too large
through later life.
“At the same time, a baby of normal size at birth, but who is given too
much formula milk, which the mother will perceive as a good thing - i.e.
that the baby is growing fast - in clinical terms it may potentially be
growing too fast.
“That baby may be at more risk of later disease because when you grow too
rapidly one of the adaptations is you lay down too much fat. Once you have
too much fat in early life that can stay with you throughout your life: you
may become obese earlier with all the complications that go with that.”
EARNEST is a Europe-wide project bringing together scientists from 38
research institutions across 16 countries in the fields of genetics,
molecular biology, epidemiology, public health and consumer behaviour.
Professor Berthold Koletzko, of the University of Munich, is co-ordinating
the six research initiatives that make up the EARNEST project.
Professor Koletzko said: “Major differences in risk factors for
significant health problems - such as cardiovascular disease, diabetes,
obesity, bone health, immune function, cognitive development and behaviour -
have already been observed in children who experienced different diets in
the first few months of life, or whose mothers were given different
supplements during pregnancy.
“These studies have not been running long enough to know whether the
differences seen in childhood persist into adult life. If they do, the
impact on the health of future generations is enormous.”
UNIVERSITY OF NOTTINGHAM
University Park
Nottingham
NG7 2RD
http://www.nottingham.ac.uk
( Maart 2006)