Omega-3
vetzuren tegen hartritmestoornissen.*
Uit
een kleine studie onder 50 ouderen in de leeftijd van 81-83 jaar blijkt dat
omega-3 vetzuren zorgen voor een stabiel hartritme en daarmee de kans op een
mogelijk hartaanval of hartstilstand sterk verkleinen.
Fish
Oil Prevents Potentially Deadly Heart Rate Variability
A
two-gram fish oil supplement given daily to elderly persons prevented a decline
in heart rate variability caused by tiny, dangerous airborne pollutant particles.
Heart rate variability, a measure of the autonomic nervous system's regulation
of the heart, is an independent risk factor for cardiac arrhythmias, heart
attack
or sudden death.
These findings appeared in the second issue of the December 2005 American
Journal of Respiratory and Critical Care Medicine, published by the American
Thoracic Society.
Fernando Holguin, M.D., of the Centers for Disease Control and Prevention in
Atlanta, Georgia, and eight associates provided fish oil supplements to 26
residents of a nursing home in Mexico City. A control group of 24 residents was
given soy oil supplements. The participants' average age ranged from 81 to 83
years old.
"In this randomized controlled trial, fish oil supplementation prevented
the reduction in heart rate variability associated with the same-day exposure to
indoor particulate matter," said Dr. Holguin. "In contrast, soy oil,
our comparison supplementation of plant-derived polyunsaturated fatty acids, was
associated with a marginal, nonsignificant protection from the effects of
particulate matter on heart rate variability."
"Fish oil as a source of omega-3 polyunsaturated fatty acids could be
considered as a potential form of preventive measure to reduce the risk of
arrhythmia and sudden death in elderly subjects exposed to ambient air pollution,"
said Dr. Holguin.
In the study, the residents were exposed to tiny indoor air pollutant particles
that had a dimension of 2.5 micrograms or less. All participants spent 92
percent of their time indoors.
The supplement study was conducted over six months. None of the patients
suffered from cardiac arrhythmias, had a pacemaker or were being treated with
oral anticoagulants.
Participants had their heart rate variability checked between 8 a.m. and 1 p.m.
on alternate weekdays. To ensure accurate measurement, the subjects lay flat on
their back five minutes before starting the test. Each electronic analysis
lasted 6 minutes as each participant rested.
Prior to the beginning of the study, all participants had a low intake of
omega-3 polyunsaturated fatty acids.
The authors called for larger studies to confirm their results.
Contact: Fernando Holguin, M.D., 1600 Clifton Road N. E., MSE-17, Atlanta, GA
Suzy Martin
smartin@thoracic.org
American Thoracic Society
http://www.thoracic.org
( December 2005) (Opm.
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