Cacao
en zwarte chocolade bij diarree.*
Bij
diarree wordt door de darmen veel vocht uitgescheiden. Dit wordt door een enzym
(CFTR) in de darmen geregeld. Uit wetenschappelijk onderzoek nu blijkt dat de
flavonoïden in zwarte chocola (en cacao) dit enzym kunnen binden en afremmen
waardoor de vochtafscheiding duidelijk afneemt. Drink trouwens bij diarree
altijd ruim voldoende water en/of thee om het vochtverlies te compenseren.
Dark
Chocolate Helps Diarrhea: Study Confirms Ancient Myth
--
A new study conducted by researchers at Children's Hospital & Research
Center Oakland is the first to discover that a chemical in cocoa beans can limit
the development of fluids that cause diarrhea. Cocoa
beans contain a large amount of chemicals called flavonoids. Scientists believe
that these flavonoids can be used to create natural supplements
to ease diarrhea symptoms. Dark chocolate contains high concentrations of cocoa
and may offer mild relief.
The
study, published in the October issue of The Journal of Nutrition,
found that cocoa flavonoids can bind to and inhibit a protein in the intestines
called CFTR, which regulates fluid secretion in the small intestines. The
research was done in collaboration with scientists at Heinrich Heine University
in Germany. "Our study presents the first evidence that fluid loss by the
intestine can be prevented by cocoa flavonoids," said Horst Fischer, Ph.D.,
Associate Scientist, Children's Hospital Oakland Research Institute and
co-author of the study. "Ultimately, this discovery could lead to the
development of natural treatments that are
inexpensive, easy to access and are unlikely to have side effects."
Each
year, Americans record an average of 2.4 million visits to their doctor
with symptoms of diarrhea. Children younger than the age of five and the elderly
are the most likely to develop grave health problems if their condition leads to
dehydration. "Patients with diarrhea can lose dangerous amounts of fluids,"
said Beate Illek, Ph.D., Associate Scientist, Children's Hospital Oakland
Research Institute and co-author of the study. In severe cases children or
elderly patients with diarrhea can die from dehydration within a few days.
History shows that the use of cocoa to treat diarrhea dates back to the 16th century by ancient South American and European cultures. Until now, no one knew exactly why the cocoa bean appeared to be a remedy. "Our research successfully proves that this ancient myth is really based on scientific principals," said Dr. Illek. For more than a year, scientists tested cocoa extract and flavonoids in cell cultures that mimic the lining of the intestine. All of the cultures reported lower fluid levels. Consequently, the tests confirmed that cocoa flavonoids are a possible remedy for diarrhea. ( Okt. 2005)