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Soja goed voor cholesterol*
Uit een onderzoek onder ruim duizend vrouwen blijkt dat het
eten van soja(producten) omgekeerd eveneredig is met de hoogte van het
cholesterol. Bij inname van 6 gram per dag is het LDL (slechte cholesterol) ruim
12 % lager dan bij een inname van minder dan 0,5 gram per dag.
Soy
intake and blood cholesterol concentrations: a cross-sectional study of 1033
pre- and postmenopausal women in the Oxford arm of the European Prospective
Investigation into Cancer and Nutrition1,2,3
Magdalena
S Rosell, Paul N Appleby, Elizabeth A Spencer and Timothy J Key
1
From the Cancer Research UK Epidemiology Unit, University of Oxford, Oxford,
United Kingdom
Background:
Clinical trials have suggested that the intake of soy protein reduces blood
cholesterol. Few studies have explored this relation in subjects who consume soy
as part of their regular diet.
Objective:
In this study, we investigated whether blood cholesterol concentrations are
related to the intake of soyfoods in a cohort comprising subjects with a wide
variation in soy intake.
Design:
This cross-sectional study included 1033 pre- and postmenopausal women selected
from the Oxford arm of the European Prospective Investigation into Cancer and
Nutrition. The sample included 361 nonvegetarians, 570 vegetarians, and 102
vegans. Their dietary intake was assessed by using a food-frequency
questionnaire. Anthropometric data, medical history, and lifestyle information
were obtained with the use of a questionnaire, blood samples were obtained, and
plasma total, LDL-, and HDL-cholesterol concentrations were measured.
Results:
Soy-protein intake was inversely associated with total and LDL-cholesterol
concentrations and with the ratio of total to HDL cholesterol but not with
HDL-cholesterol concentrations. Mean plasma LDL-cholesterol concentrations in
women with a soy-protein intake
6 g/d was 12.4% lower than that in women who consumed <0.5 g/d (P <
0.001).
Conclusion:
Moderate intakes of soyfoods as part of a regular diet are associated with
favorable blood cholesterol concentrations.
American Journal of Clinical Nutrition, Vol. 80, No. 5, 1391-1396, November 2004