(Koude) Groentesoep heel gezond*.
Soep van rauwe groenten ook wel Gazpacho genoemd verhoogt
duidelijk de bloedwaarden aan vitamine C en vermindert oxidatieschade en
bepaalde ontstekingsmarekers.
Consumption
of Vegetable Soup Increases Plasma Vitamin C and Decreases Oxidative Stress and
Inflammatory Biomarkers in Healthy Humans1
Concepción
Sánchez-Moreno*,, M. Pilar Cano Begoña de Ancos
,
Lucía Plaza, Begoña Olmedilla**, Fernando Granado** and
Antonio Martín*,2
*
Nutrition and Neurocognition Laboratory, Jean Mayer U.S. Department of
Agriculture-Human Nutrition Research Center on Aging at Tufts University,
Boston, MA;
Department
of Plant Foods Science and Technology, Instituto del Frío-CSIC, Madrid, Spain;
and ** Unit of Vitamins, Section of Nutrition, Clínica Puerta de
Hierro, Madrid, Spain
2To
whom correspondence should be addressed. E-mail:
antonio.martin@tufts.edu.
Current
evidence supports a significant association between fruit and
vegetable intake and health. In this study, we assessed the effect of
consuming a vegetable-soup "gazpacho" on vitamin C and
biomarkers of oxidative stress and inflammation in a healthy human
population. We also examined the association between vitamin C and F2-isoprostanes
(8-epiPGF2a
),
uric acid (UA), prostaglandin E2 (PGE2),
monocyte chemotactic protein-1 (MCP-1), and the cytokines, tumor
necrosis factor-
a
(TNF-
a),
interleukin-1ß (IL-1ß), and IL-6. Gazpacho is a Mediterranean dish
defined as a ready-to-use vegetable soup, containing
80%
crude vegetables rich in vitamin C. Subjects (6 men, 6 women)
enrolled in this study consumed 500 mL/d of gazpacho corresponding to
an intake of 72 mg of vitamin C. On d 1, subjects consumed the
gazpacho in one dose; from d 2 until the end of the study, d 14, 250
mL was consumed in the morning and 250 mL in the afternoon. Blood was
collected before drinking the soup (baseline) and on d 7 and 14.
Baseline plasma vitamin C concentrations did not differ between men
and women (P = 0.060). Compared with baseline, the vitamin C
concentration was significantly higher on d 7 and 14 of the
intervention in both men and women (P < 0.05). Baseline
plasma levels of UA and F2-isoprostanes were higher (P
0.002)
in men than in women. The F2-isoprostanes decreased on d
14 in men and women (P
0.041),
and UA decreased in men (P = 0.028). The concentrations of
vitamin C and 8-epiPGF2a
were inversely correlated (r = –0.585, P = 0.0002).
Plasma PGE2 and MCP-1 concentrations decreased in men and
women (P
0.05)
on d 14, but those of TNF-a
,
IL-1ß, and IL-6 did not change. Consumption of the vegetable soup
decreases oxidative stress and biomarkers of inflammation, which
indicates that the protective effect of vegetables may extend beyond
their antioxidant capacity.
The
American Society for Nutritional Sciences J. Nutr. 134:2899-2902, November 2004
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