Flavonoïden uit fruit en groente worden snel opgenomen in de bloedbaan.*

Uit een studie onder ratten blijkt dat flavonoïden, zoals anthocyanides in druiven, wijn, bessen en andere fruit en groente na consumptie binnen een tiental minuten opgenomen worden in de bloedbaan tot zelfs in de hersenen.

Fast Access of Some Grape Pigments to the Brain

Sabina Passamonti, Urska Vrhovsek, Andreja Vanzo, # and Fulvio Mattivi*

Dipartimento di Biochimica Biofisica e Chimica delle Macromolecole, Università di Trieste, via L. Giorgeri 1, 34127 Trieste, Italy; Istituto Agrario di San Michele all'Adige (IASMA), Centro Sperimentale, via E. Mach 2, 38010 San Michele all'Adige, Italy; and Kmetijski Institut Slovenije, Hacquetova 17, 1001 Ljubljana, Slovenia

Abstract:

Anthocyanins represent the main flavonoid pigments in red grape and wine, in red berries, and in many other fruits and vegetables and are widespread in the human diet. After ingestion, these complex, hydrophilic compounds quickly appear as intact molecules in the plasma. This study investigated their presence in the brain of anesthetized rats that received 8 mg/kg of body weight of a pure anthocyanin mixture extracted from Vitis vinifera grapes. The mixture was maintained in the stomach for 10 min. After this time, intact anthocyanins were detected by HPLC-DAD-MS not only in the plasma (176.4 ± 50.5 ng/mL, mean ± SEM) but also in the brain (192.2 ± 57.5 ng/g). These results demonstrate for the first time that grape pigments can reach the mammalian brain within minutes from their introduction into the stomach. (Aug. 2005)